Wilson Wolf Manufacturing

Celline Overview, Application Introduction

• M. Wolf; Wilson Wolf Corporation, Minneapolis USA

This report is an overview of the CELLine regarding its operation and the principle of cell compartment viable cell capacity. This report describes the impact of nutrient medium exchange and the diffusion of solute across the semi permeable membrane. The importance of inoculation density and its impact on culture initiation is described. The variable volume of the cell compartment, expected osmotic water flux, and equivalency between the different CELLine models is also reported.