G-Rex is our Revolutionary Manufacturing Solution for Cell Therapy
Wilson Wolf created a paradigm shift in cell culture device design that disrupts age old beliefs regarding cell production.
Historic designs such as T-flasks, spinner flasks, gas permeable bags, and WAVE bioreactors rely on an old paradigm that diffusion is responsible for cell access to nutrients. Wilson Wolf has discovered that convection, not diffusion, is the key to achieving maximum cell growth with uninterrupted access to nutrients.
Furthermore, diffusion greatly limits the medium volume in a device unless the medium is physically mixed.
When compared to age-old designs, Wilson Wolf’s revolutionary designs provide the easiest and fastest way to generate the most cells in the least amount of space.
By discovering that convection governs nutrient transport, not diffusion, we are revolutionizing device design to provide advantages not previously possible.
Wilson Wolf’s revolutionary products include unique geometry that allows medium to reside at heights not previously possible with conventional methods. And, unlike any other device, G-Rex® geometry provides cells with virtually unlimited access to oxygen and nutrients on demand.
See the G-Rex Revolution in Action
Cell Therapy Manufacturing Made Easy
G-Rex automatically provides unlimited oxygen and nutrients on demand for auto and allo CAR T, TCR, TIL, NK, T reg, and HSC.
G-Rex combines key benefits that are not possible with competitive CGT manufacturing technology:
- Closed system activation, transduction, expansion, and concentrate with virtually no human intervention.
- More cells in less space allows highly efficient use of facilities.
- Most efficient use of reagents.
- Simple and linear scale up. Protocols in a small device translate linearly to larger devices.
- Highly efficient scale out. Just one small device per patient.